| Description | 1,6-O,O-Diacetylbritannilactone(OODBL) has anti-inflammatory activity, it has a potential therapeutic efficacy on inflammatory diseases especially allergic airway disease as a lead compound. OODBL has anti-asthmatic activity, it reduces leukotriene C4 production and degranulation through the suppression of cytosolic phospholipase A2 phosphorylation and phospholipase Cγ-mediated Ca2+ influx in IgE/antigen-stimulated BMMCs. OODBL also exhibits potent antitumor activity against several human cancer cell lines. |
| Synonyms | 1,6-O,O-Diacetylbritannilactone |
| molecular weight | 350.41 |
| Molecular formula | C19H26O6 |
| CAS | 1286694-67-4 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |