| Description | Bongkrekic acid (Bongkrekic Acid (ammonium salt)) is a mitochondrial toxin secreted by Burkholderia gladioli that inhibits adenine nucleotide translocase (ANT).Bongkrekic acid Bongkrekic acid Bongkrekic acid induces extracellular traps in neutrophils through signaling mediated by p38, ERK, PAD4, and P2X1. |
| Synonyms | Bongkrek Acid |
| molecular weight | 486.6 |
| Molecular formula | C28H38O7 |
| CAS | 11076-19-0 |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 80 mg/mL (164.40 mM), Sonication is recommended. H2O: 1 mg/mL |
| References | 1. Anwar M,et al. Bongkrekic Acid-a Review of a Lesser-Known Mitochondrial Toxin. J Med Toxicol. 2017 Jun;13(2):173-179. doi: 10.1007/s13181-016-0577-Epub 2017 Jan 19. 2. Han D, et al. Bongkrekic Acid and Burkholderia gladioli pathovar cocovenenans: Formidable Foe and Ascending Threat to Food Safety. Foods. 2023 Oct 26;12(21):3926. 3. Kano A,et al. Bongkrekic acid facilitates glycolysis in cultured cells and induces cell death under low glucose conditions. Biochem Biophys Rep. 2019 Aug 29;20:100683. |