| Description | α-Factor Mating Pheromone, yeast acetate (Mating Factor α acetate) is a peptide of 13 amino acids secreted by Saccharomyces cerevisiae α cells. |
| In vitro | α-Factor Mating Pheromone（酵母）由MATα细胞持续合成，并作用于MATa细胞[1]。它能抑制酵母a细胞的分裂周期，并与haploid a细胞中的35S-α-factor竞争结合，结合常数Kd为0.3 μM。这种结合与五种温度敏感的ste2突变体有关，且具有热不稳定性。然而，α-Factor Mating Pheromone（酵母）与其他温度敏感突变体（ste4, ste5, ste7, ste11, 和 ste12）的结合活性表现出无温度敏感性[2]。 |
| Synonyms | Mating Factor α acetate, α-Factor Mating Pheromone, yeast acetate(59401-28-4 free base) |
| molecular weight | 1744.05 |
| Molecular formula | C84H118N20O19S |
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Naider F, et al. The alpha-factor mating pheromone of Saccharomyces cerevisiae: a model for studying the interaction of peptide hormones and G protein-coupled receptors. Peptides. 2004 Sep;25(9):1441-63. |