| Description | Aloin (Aloin-A)(mixture of A&B), a natural anthracycline from Aloe vera, is a tyrosinase inhibitor. |
| In vivo | 在MCF-7细胞系中,Aloin通过诱导细胞凋亡引起处于有丝分裂期的细胞比率减少,抑制拓扑IIα蛋白表达,并下调细胞周期B1蛋白的表达。HeLaS3细胞中,Aloin在生理浓度(IC50=97 μM)下表现出明显的抗增殖作用,导致细胞周期阻滞在S期,明显增加细胞凋亡。 |
| Synonyms | Barbaloin, 芦荟素, Barbalin, Aloin-A, Aloin(mixture of A&B), Barbaloin-A, 芦荟甙 |
| molecular weight | 418.39 |
| Molecular formula | C21H22O9 |
| CAS | 1415-73-2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | Ethanol: 2 mg/mL (4.78 mM) H2O: 1 mg/mL (2.39 mM) DMSO: 4.18 mg/mL (10 mM), Sonication is recommended. |
| References | 1. Tan C, et al. Chin Med J (Engl), 2002, 115(12), 1859-1862. |