| Description | Alamethicin is a channel-forming antibiotic peptide isolated from Trichoderma viride with potential antimicrobial activity, inhibits methanogenesis and promotes acetogenesis in bioelectrochemical systems. alpha-Amanitin (BI-9627) is a channel-forming antibiotic peptide isolated from Trichoderma viride. |
| molecular weight | 1964.31 |
| Molecular formula | C92H150N22O25 |
| CAS | 27061-78-5 |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Rindfleisch H, et al. Biosynthesis of alamethicin. FEBS Lett. 1976 Mar 1;62(3):276-80. 2. Olga S.Ostroumova, et al. Chapter Six - Modifiers of Membrane Dipole Potentials as Tools for Investigating Ion Channel Formation and Functioning. International Review of Cell and Molecular Biology Volume 315, 2015, Pages 245-297. 3. Sansom MS, Tieleman DP, Berendsen HJ. The mechanism of channel formation by alamethicin as viewed by molecular dynamics simulations. Novartis Found Symp. 1999;225:128-41; discussion 141-5. |