| Description | Adenosylcobalamin (AdoCbl) is a biologically active form of vitamin B12 .It is a cofactor for methylmalonyl CoA mutase. It belongs to the corrinoid group of compounds, which contain a corrin macrocycle, and is produced only by certain bacteria and archaea. It is a cofactor for various enzymes including mutases, eliminases, aminomutases, and a reductase. |
| In vitro | Adenosylcobalamin acts as the cofactor for a group of enzymes that catalyze unusual rearrangement or elimination reactions[1]. |
| Synonyms | Cobamamide, Coenzyme B12, 腺苷钴胺, AdoCbl |
| molecular weight | 1579.58 |
| Molecular formula | C72H100CoN18O17P |
| CAS | 13870-90-1 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | H2O: 4 mg/mL(2.53 mM) |
| References | 1. Kumudha A, et al. Characterization of vitamin B12 in Dunaliella salina. J Food Sci Technol. 2016 Jan;53(1):888-94. 2. Marsh EN, et al. Adenosylcobalamin enzymes: Theory and experiment begin to converge. Biochim Biophys Acta. 2012 Nov;1824(11):1154-64. |