| Description | Acerinol is an active ingredient from traditional Chinese medicinal herbs. It could be used as a cancer multidrug resistance reversal agent. Acerinol can significantly stimulate the activity of ABCB1 ATPase without affecting the expression of ABCB1 on neither mRNA nor protein level. |
| molecular weight | 486.68 |
| Molecular formula | C30H46O5 |
| CAS | 19902-53-5 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Liu DL, Li YJ, Yao N, Xu J, Chen ZS, Yiu A, Zhang CX, Ye WC, Zhang DM. Acerinol, a cyclolanstane triterpenoid from Cimicifuga acerina, reverses ABCB1-mediated multidrug resistance in HepG2/ADM and MCF-7/ADR cells. Eur J Pharmacol. 2014 Jun 15;733:34-44. doi: 10.1016/j.ejphar.2014.03.043. Epub 2014 Apr 4. PubMed PMID: 24704556. |