| Description | 6-Methoxytricin, a flavonoid isolated from Centella asiatica, is an inhibitor of aldose reductase (AR) and advanced glycosylation end-products (AGE), and inhibits T-cell proliferation and activation in biologic cells. |
| In vitro | 6-Methoxytricin对刀豆蛋白concanavalin A (Con A)诱导的T细胞增殖有明显的抑制作用，IC50值为1.4 μM[2]。 |
| Target activity | AR:30.29 μM, AGE:134.88 μM |
| molecular weight | 360.31 |
| Molecular formula | C18H16O8 |
| CAS | 76015-42-4 |
| Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Lee YK, et al. Inhibitory Effect of Chemical Constituents Isolated from Artemisia iwayomogi on Polyol Pathway and Simultaneous Quantification of Major Bioactive Compounds. Biomed Res Int. 2017;2017:7375615. 2. Yin Y,et al. Anti-inflammatory and immunosuppressive effect of flavones isolated from Artemisia vestita. J Ethnopharmacol. 2008 Oct 30;120(1):1-6. |