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6-Methoxyflavanone

CAS No.: 3034-04-6

6-Methoxyflavanone (6-MeOF) is A positive allosteric modulator of the GABA response of human recombinant GABA A receptor
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Description 6-Methoxyflavanone (6-MeOF) is A positive allosteric modulator of the GABA response of human recombinant GABA A receptor, with antianxiety and anti-inflammatory activity, and can be used to reduce cisplatin induced neuropathic pain.
Synonyms NSC50184
molecular weight 254.28
Molecular formula C16H14O3
CAS 3034-04-6
Storage store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility DMSO: 15 mg/mL (58.99 mM), Sonication is recommended.
References 1. Akbar S,et al. Characterization of 6-methoxyflavanone as a novel anxiolytic agent: A behavioral and pharmacokinetic approach. Eur J Pharmacol. 2017 Apr 15;801:19-27. 2. Roland WS,et al. 6-methoxyflavanones as bitter taste receptor blockers for hTAS2R39. PLoS One. 2014 Apr 10;9(4):e94451.