| Description | 6-(Dimethylamino)purine (N,N-Dimethyladenine) is a serine threonine protein kinase and CDK inhibitor |
| In vitro | The apoptosis was induced by 6-dimethylaminopurine(6-DMAP) in a dose- and time-dependent manner and treatment for 16 h at a concentration of 5 mM induced apparent DNA fragmentation, phosphatidylserine externalization and lowering of the mitochondrial membrane potential, which are typical markers of apoptosis[1]. |
| Synonyms | N,N-Dimethyladenine, 6-二甲基氨基嘌呤 |
| molecular weight | 163.18 |
| Molecular formula | C7H9N5 |
| CAS | 938-55-6 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 32mg/mL(196.1mM) |
| References | 1. Nakashima M , Cui Z G , Tabuchi Y , et al. Apoptosis induced by an alkylated purine, 6-dimethylaminopurine, and changes in gene expression in human lymphoma U937 cells[J]. Anticancer research, 2008, 28(2A):609-620. 2. Neant I , Guerrier P . 6-Dimethylaminopurine blocks starfish oocyte maturation by inhibiting a relevant protein kinase activity[J]. Experimental Cell Research, 1988, 176(1):0-79. |