| Description | 6-Biopterin (L-Biopterin) is a natural product,is a NO synthase cofactor. |
| In vitro | The oxidized cofactor 6-biopterin (0.2 x 10(-6) M) is extremely cytotoxic to human melanocytes under in vitro conditions.?Consequently, its reduction to 6-BH4 via q-BH2 is essential to melanocyte viability.human thioredoxin reductase has the capacity to reduce 6-biopterin to q-BH2 where further reduction to 6-BH4 follows via dihydropteridine reductase or reduced glutathione[1]. |
| Synonyms | L-生物喋呤, L-Biopterin |
| molecular weight | 237.22 |
| Molecular formula | C9H11N5O3 |
| CAS | 22150-76-1 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 6 mg/mL (25.29 mM) |
| References | 1. Schallreuter K U , Buttner G , Pittelkow M R , et al. Cytotoxicity of 6-Biopterin to Human Melanocytes[J]. Biochemical & Biophysical Research Communications, 1994, 204(1):0-48. 2. Longo N . Disorders of biopterin metabolism[J]. Journal of Inherited Metabolic Disease, 2009, 32(3):457-457. |