| Description | 5-Methyltetrahydrofolic acid (5-Methyl THF) is a biologically active form of folic acid and a methylated derivate of tetrahydrofolate. It is the predominant natural dietary folate and the principal form of folate in plasma and cerebrospinal fluid. |
| Synonyms | 甲基叶酸盐, 5-Methyl THF |
| molecular weight | 459.46 |
| Molecular formula | C20H25N7O6 |
| CAS | 134-35-0 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 55 mg/mL (119.71 mM), Sonication is recommended. |
| References | 1. Wright AJ, et al. Comparison of (6 S)-5-methyltetrahydrofolic acid v. folic acid as the reference folate in longer-term human dietary intervention studies assessing the relative bioavailability of natural food folates: comparative changes in folate status following a 16-week placebo-controlled study in healthy adults. Br J Nutr. 2010 Mar;103(5):724-9. |