| Description | 5-Methoxyindole-3-acetic acid (5-Methoxyindoleacetic acid) is a metabolite of Melatonin and is isolated from pineal tissue. |
| In vivo | 经胎盘给药的5-Methoxyindole-3-acetic acid 具有诱发细胞繁殖的活性，在84%的C57BL/6小鼠后代中引发了恶性和良性肿瘤（淋巴肉瘤、腺瘤、肝瘤及其他肿瘤）的发展。与对照组相比，5-Methoxyindole-3-acetic acid 组肿瘤的数量显著增多，并且出现得更早，恶性程度更高[2]。 |
| Synonyms | Methoxyindoleacetic acid, 5-Methoxyindoleacetic acid, 5-甲氧基吲哚-3-乙酸 |
| molecular weight | 205.21 |
| Molecular formula | C11H11NO3 |
| CAS | 3471-31-6 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 88 mg/mL (428.83 mM) |
| References | 1. Yáñez J, Meissl H. Secretion of the methoxyindoles melatonin, 5-methoxytryptophol, 5-methoxyindoleacetic acid, and 5-methoxytryptamine from trout pineal organs in superfusion culture: effects of light intensity. Gen Comp Endocrinol. 1996 Feb;101(2):165-72. 2. Malakhova NV, Raushenbakh MO. Transplatsentarnoe kantserogennoe vozdeĭstvie proizvodnogo serotonina 5-metoksiindolil-3-uksusnoĭ kisloty [Transplacental carcinogenic effect of the serotonin derivative 5-methoxyindoleacetic acid]. Biull Eksp Biol Med. 1986 May;101(5):605-7. Russian. |