| Description | 4-Pentynoic acid (Propargylacetic acid) has been used in reactions with 1-bromo-1-alkynes in the presence of a Pd catalyst yields biologically active ynenol lactones. It also is used in a synthesis of a cytotoxic macrolide by ring-closing metathesis of a bis acetylene. |
| Synonyms | Propargylacetic acid, 戊炔酸 |
| molecular weight | 98.1 |
| Molecular formula | C5H6O2 |
| CAS | 6089-09-4 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 45 mg/mL (458.71 mM) |
| References | 1. Fuller, R., Snoddy, H., Roush, B., & Molloy, B. (1973). Elevation of hepatic tyrosine 2-oxoglutarate aminotransferase in rats by 4-pentynoic acid, a hypoglycemic agent. Experientia, 29(3), 277-278. doi: 10.1007/bf01926473 |