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3-Butylidenephthalide

CAS No.: 551-08-6

1. 3-Butylidenephthalide (Butylidene phthalide) has antihyperglycemic effect is due to inhibition of α-glucosidase at t
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Description 1. 3-Butylidenephthalide (Butylidene phthalide) has antihyperglycemic effect is due to inhibition of α-glucosidase at the intestinal level, inhibited the activity of yeast-α-glucosidase (IC(5) 2.35 mM) in a noncompetitive fashion with a K(i) of 4.86 mM.
Synonyms Butylidene phthalide, n-Butylidenephthalide, 丁烯基苯酞, 丁烯基苯酞;丁烯基酞内酯
molecular weight 188.22
Molecular formula C12H12O2
CAS 551-08-6
Storage keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility DMSO: 45 mg/mL (239.07 mM)
References 1. Saw C L L , Qing W , Zheng-Yuan S , et al. Effects of natural phytochemicals in Angelica sinensis (Danggui) on Nrf2-mediated gene expression of phase II drug metabolizing enzymes and anti-inflammation[J]. Biopharmaceutics & Drug Disposition, 2014, 34(6):303-311.