Description | 5,7,3',5'-tetrahydroxy-6,4'-dimethoxyflavone exhibits anti-HIV-1 activity in the anti-syncytium assay using (∆Tat/rev)MC99 virus and 1A2 cell line system, it shows considerably activity against HIV-1 reverse transcriptase. It exhibits cytotoxic activity against P-388 cell lines, it can inhibit DNA topoisomerase IIα activity, which may be responsible for the observed cytotoxicity. |
molecular weight | 346.29 |
Molecular formula | C17H14O8 |
CAS | 125537-92-0 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |