| Description | 3,4'-Dihydroxyflavone (3,4'-DHF) is an oral active flavonoid. 3,4'-Dihydroxyflavone (3,4'-DHF) shows antiviral activity against Influenza A virus. |
| In vivo | 3,4'-Dihydroxyflavone (3,4'-DHF; PO, 1 mg/kg per 30 μL, daily, 5 days) significantly decreases virus titers and pathological changes in the lung and reduced body weight loss and death[1] |
| Animal experiments | Animal Model: 3,4'-Dihydroxyflavone (3,4'-DHF; PO,1 mg/kg per 30 μL,daily,5 days) significantly decreases virus titers and pathological changes in the lung and reduced body weight loss and death[1].Dosage: 1 mg/kg per 30 μL. Administration: Oral administration daily for 5 days. |
| molecular weight | 254.24 |
| Molecular formula | C15H10O4 |
| CAS | 14919-49-4 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 155 mg/mL (69.66 mM) |
| References | 1. Hossain MK, et al. Antiviral activity of 3,4'-dihydroxyflavone on influenza a virus. J Microbiol. 2014 Jun;52(6):521-6. |