| Description | 3,4-Dihydroxybenzeneacetic acid (3,4-Dihydroxyphenylacetic acid) is the main metabolite of dopamine. |
| In vitro | Cerebrospinal fluid (CSF) 3,4-Dihydroxybenzeneacetic acid (DOPAC) is derived from the intra-neuronal metabolism of cytoplasmic dopamine and acts as a sensitive and specific biomarker of central dopamine deficiency[1]. |
| Synonyms | DOPAC, 3,4-Dihydroxyphenylacetic acid, 3,4-二羟基苯乙酸 |
| molecular weight | 168.15 |
| Molecular formula | C8H8O4 |
| CAS | 102-32-9 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | H2O: 10 mg/mL DMSO: 50 mg/mL (297.35 mM) |
| References | 1. Goldstein DS, et al. Elevated cerebrospinal fluid ratios of cysteinyl-dopamine/3,4-dihydroxyphenylacetic acid in parkinsonian synucleinopathies. Parkinsonism Relat Disord. 2016 Oct;31:79-86. |