| Description | 1-Methylhistamine dihydrochloride is a major metabolite of histamine by histamine N-methyltransferase in the pathway of histidine metabolism. It has been used as a biomarker of histaminergic system activity in the brains of Alzheimer's disease patients as well as those with hypersomnia and other neurological conditions. |
| molecular weight | 198.09 |
| Molecular formula | C6H13Cl2N3 |
| CAS | 6481-48-7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 12 mg/mL (60.58 mM) |
| References | 1. Saito K, et al. Determination of urinary excretion of histamine and 1-methylhistamine by liquid chromatography. J Chromatogr B Biomed Appl. 1994 Apr 1;654(2):270-5. |
1-Methylhistamine dihydrochloride
CAS No.: 6481-48-7
1-Methylhistamine dihydrochloride is a major metabolite of histamine by histamine N-methyltransferase in the pathway of
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