| Description | 1-Methyl-2-undecyl-4(1H)-quinolone, and dihydroevocarpine should also be served as the chemical markers together with evodiamine for the quality control of Evodia rutaecarpa (Juss.) Benth. 1-Methyl-2-undecyl-4(1H)-quinolone shows a selective inhibition of type B MAO (MAO-B) activity with the IC(50) value of 15.3 microM using a substrate kynuramine, but does not inhibit type A MAO (MAO-A) activity.It can mitigate high phosphate-induced human aortic valve interstitial cells (HAVICs) calcification by inhibiting phosphate cotransporter (PiT-1) gene expression. It also shows moderate antiangiogenic activity against human tumor cells. |
| Target activity | MAO-B:15.3 μM (IC50), MAO-B:9.91 μM (Ki) |
| Synonyms | 1-Methyl-2-undecylquinolin-4(1H)-one |
| molecular weight | 313.48 |
| Molecular formula | C21H31NO |
| CAS | 59443-02-6 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
1-Methyl-2-undecyl-4(1H)-quinolone
CAS No.: 59443-02-6
1-Methyl-2-undecyl-4(1H)-quinolone, and dihydroevocarpine should also be served as the chemical markers together with ev
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