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1-Hydroxyrutaecarpine

CAS No.: 53600-24-1

1-Hydroxyrutaecarpine exhibits cytotoxicities (ED50 values4 microg/mL) against P-388 or HT-29 cell lines in vitro.
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Description 1-Hydroxyrutaecarpine exhibits cytotoxicities (ED50 values < 4 microg/mL) against P-388 or HT-29 cell lines in vitro.
In vitro Three new alkaloids, 7,8-dehydro-1-methoxyrutaecarpine, isodecarine, and 8-demethyloxychelerythrine, together with sixteen known compounds, norchelerythrine, oxychelerythrine, decarine, dihydrocherythrinylacetaldehyde, 6-acetonyldihydrochelerythrine, rutaecarpine, 1-Hydroxyrutaecarpine, gamma-fagarine, skimmianine, (-)-matairesinol, (-)-isoarctigenin, (+)-epipinoresinol, d-sesamin, lupeol, canthin-6-one, and arnottianamide have been isolated from the root bark of Zanthoxylum integrifoliolum. The structures of these new compounds were determined through spectral analyses[1]
molecular weight 303.321
Molecular formula C18H13N3O2
CAS 53600-24-1
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year
References 1. New indolopyridoquinazoline, benzo[c]phenanthridines and cytotoxic constituents from Zanthoxylum integrifoliolum.Planta Med. 2005 May;71(5):470-5.