| Description | 1,3-Dithiane (1,3-Dithian) is a protected formaldehyde anion equivalent that could serve as a useful labeled synthon. 1,3-Dithiane is also a sulfur-containing Maillard reaction products found in boiled beef extracts. |
| In vitro | 1,3-Dithiane shows potent direct-acting mutagenicity toward S. typhimurium TA98 and TA100 [2]. |
| Synonyms | 1,3-Dithian, M-DITHIANE, 1,3-Dithiacyclohexane, 1,3-二噻烷 |
| molecular weight | 120.24 |
| Molecular formula | C4H8S2 |
| CAS | 505-23-7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 55 mg/mL (457.42 mM) |
| References | 1. Lee H, et al. Genotoxicity of 1,3-dithiane and 1,4-dithiane in the CHO/SCE assay and the Salmonella/microsomal test. Mutat Res. 1994 Jun;321(4):213-8. 2. Martinez RA, et al. Synthesis of isotopically labeled 1,3-dithiane. J Labelled Comp Radiopharm. 2014 May 15;57(5):338-41. |