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ε-Rhodomycinone

CAS: 21288-60-8 F: C22H20O9 W: 428.39

ε-Rhodomycinone is a bacterial metabolite found in S. griseoruber. It is a precursor to Rhodomycin D, which is an inter
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Bioactivity ε-Rhodomycinone is a bacterial metabolite found in S. griseoruber. It is a precursor to Rhodomycin D, which is an intermediate in the bioconversion of ε-rhodomycinone to Daunorubicin (HY-13062) and Doxorubicin (HY-15142R)[1][2][3].
CAS 21288-60-8
Formula C22H20O9
Molar Mass 428.39
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Podojil M, et al. Production of rhodomycins in Streptomyces griseoruber 4620. Folia Microbiol (Praha). 1980;25(6):464-6. [2]. Olano C, et al. A two-plasmid system for the glycosylation of polyketide antibiotics: bioconversion of epsilon-rhodomycinone to rhodomycin D. Chem Biol. 1999 Dec;6(12):845-55. [3]. Dickens ML, et al. In vivo and in vitro bioconversion of epsilon-rhodomycinone glycoside to doxorubicin: functions of DauP, DauK, and DoxA. J Bacteriol. 1997 Apr;179(8):2641-50.