Bioactivity | μ-Conotoxin BuIIIB (Mu-Conotoxin BuIIIB) is a mammalian neuronal voltage-gated sodium channel (VGSC) blocker. μ-Conotoxin BuIIIB can be obtained from the venom of Cone snails and is a probe for ion channel function research. μ-Conotoxin BuIIIB can be used in the study of neurological diseases such as pain[1]. |
Name | µ-Conotoxin BuIIIB |
CAS | 1400096-06-1 |
Sequence | Val-Gly-Glu-Arg-Cys-Cys-Lys-Asn-Gly-Lys-Arg-Gly-Cys-Gly-Arg-Trp-Cys-Arg-Asp-His-Ser-Arg-Cys-Cys-NH2 (Disulfide bridge:Cys5-Cys17, Cys6-Cys23, Cys13-Cys24) |
Shortening | VGERCCKNGKRGCGRWCRDHSRCC-NH2 (Disulfide bridge:Cys5-Cys17, Cys6-Cys23, Cys13-Cys24) |
Formula | C106H172N46O30S6 |
Molar Mass | 2763.18 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Kuang Z, et al. Mammalian neuronal sodium channel blocker μ-conotoxin BuIIIB has a structured N-terminus that influences potency. ACS Chem Biol. 2013;8(6):1344-51. |