Bioactivity | p53 (232-240) is a peptide segment of the 232-240 amino acid sequence of the human tumor suppressor protein p53. p53 (232-240) enhances its binding affinity to the Major histocompatibility complex (MHC), thereby enhancing the immunogenicity of this peptide to enhance the immune system's response to tumor antigens. p53 (232-240) can be used in the development of cancer vaccines and in the study of tumor cell recognition and clearance by the immune system[1]. |
CAS | 155314-26-4 |
Sequence | Lys-Tyr-Met-Cys-Asn-Ser-Ser-Cys-Met |
Shortening | KYMCNSSCM |
Formula | C41H67N11O14S4 |
Molar Mass | 1066.30 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Baratin M, et al. Amino acid modifications in the wild type sequence p53 232–240 overcome the poor immunogenicity of this self tumour epitope[J]. Journal of Peptide Science: An Official Publication of the European Peptide Society, 2002, 8(7): 327-334. |