Bioactivity | ddCTP is one of 2',3'-dideoxyribonucleoside 5'-triphosphates (ddNTPs) that acts as chain-elongating inhibitor of DNA polymerase for DNA sequencing. ddCTP is a nucleoside analog that targets the reverse transcriptase of human immunodeficiency virus (HIV). ddCTP can be used for AIDS research[1][2]. |
Name | ddCTP |
CAS | 66004-77-1 |
Formula | C9H16N3O12P3 |
Molar Mass | 451.16 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Z G Chidgeavadze, et al. 3'-Fluoro-2',3'-dideoxyribonucleoside 5'-triphosphates: terminators of DNA synthesis. FEBS Lett. 1985 Apr 22;183(2):275-8. [2]. Pelletier H, et al. Structures of ternary complexes of rat DNA polymerase beta, a DNA template-primer, and ddCTP. Science. 1994 Jun 24;264(5167):1891-903. |