PeptideDB

cyt-PTPε Inhibitor-1

CAS: 428478-94-8 F: C19H20N4O2S W: 368.45

cyt-PTPε Inhibitor-1 is a potent cytosolic protein tyrosine phosphatase epsilon (cyt-PTPε) inhibitor, binds to the cat
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Bioactivity cyt-PTPε Inhibitor-1 is a potent cytosolic protein tyrosine phosphatase epsilon (cyt-PTPε) inhibitor, binds to the catalytic domain of cyt-PTPε, blocks c-Src activation (dephosphorylation of c-Src), and exhibits anti-osteoclastic activity[1].
Target cyt-PTPε
Invitro cyt-PTPε Inhibitor-1 (Compound 62) is a potent cytosolic protein tyrosine phosphatase epsilon with anti-osteoclastic activity[1].
Name cyt-PTPε Inhibitor-1
CAS 428478-94-8
Formula C19H20N4O2S
Molar Mass 368.45
Appearance Solid
Transport Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Reference [1]. Ku B, et al. Identification of N-(5-(phenoxymethyl)-1,3,4-thiadiazol-2-yl)acetamide derivatives as novel protein tyrosine phosphatase epsilon inhibitors exhibiting anti-osteoclastic activity. ioorg Med Chem. 2018 Oct 1;26(18):5204-5211.