| Bioactivity | cycFWRPW is a peptide inhibitor of TLE1. TLE1 is an oncogenic transcriptional co‐repressor that exerts its repressive effects through binding of transcription factors[1]. |
| CAS | 2116533-34-5 |
| Sequence | Phe-Trp-Arg-Pro-Trp (covalent bridge:Trp2-Pro4) |
| Shortening | FWRPW (covalent bridge:Trp2-Pro4) |
| Formula | C46H56N10O6 |
| Molar Mass | 845.00 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. McGrath S, et al. Structure-Enabled Discovery of a Stapled Peptide Inhibitor to Target the Oncogenic Transcriptional Repressor TLE1. Chemistry. 2017 Jul 18;23(40):9577-9584. |
cycFWRPW
CAS: 2116533-34-5 F: C46H56N10O6 W: 845.00
cycFWRPW is a peptide inhibitor of TLE1. TLE1 is an oncogenic transcriptional co‐repressor that exerts its repressive e
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.