| Bioactivity | Z-Gly-Pro-Phe-Leu-CHO (Z-GPFL-CHO) is a tetrapeptide aldehyde that acts as a highly selective and potent proteasomal inhibitor (Ki = 1.5 µM for branched chain amino acid preferring, 2.3 µM for small neutral amino acid preferring, and 40.5 µM for chymotrypsin-like activities; IC50 = 3.1 µM for peptidyl-glutamyl peptide hydrolyzing activity)[1]. |
| Name | Z-Gly-Pro-Phe-Leu-CHO |
| CAS | 159659-05-9 |
| Sequence | Z-Gly-Pro-Phe-Leu-CHO |
| Shortening | Z-GPFL-CHO |
| Formula | C30H38N4O6 |
| Molar Mass | 550.65 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. M Orlowski, et al. Reactions of [14C]-3,4-dichloroisocoumarin with subunits of pituitary and spleen multicatalytic proteinase complexes (proteasomes). Biochemistry. 1997 Nov 11;36(45):13946-53. |
Z-Gly-Pro-Phe-Leu-CHO
CAS: 159659-05-9 F: C30H38N4O6 W: 550.65
Z-Gly-Pro-Phe-Leu-CHO (Z-GPFL-CHO) is a tetrapeptide aldehyde that acts as a highly selective and potent proteasomal inh
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.