| Bioactivity | Uniconazole, a plant growth retardant, is a potent inhibitor of abscisic acid (ABA) catabolism with an IC50 of 68 nM against ABA 8’-hydroxylase. Uniconazole is a potent competitive inhibitor of CYP707A3 activity with a Ki of 8 nM. Uniconazole evidently inhibits gibberellin biosynthesis, and brassinosteroid biosynthesis is also inhibited to some extent[1]. | ||||||||||||
| Target | IC50: 68 nM (ABA 8’-hydroxylase)Ki: 8 nM (CYP707A3 activity) | ||||||||||||
| In Vivo | Uniconazole (0-50 μM) effectively blocks ABA 8’-hydroxylase activity and enhances drought tolerance in vivo[1].Uniconazole increases the activities of antioxidant enzymes, promotes accumulation of proline and soluble sugars, and reduces accumulation of malondialdehyde[2]. Animal Model: | ||||||||||||
| Name | Uniconazole | ||||||||||||
| CAS | 83657-22-1 | ||||||||||||
| Formula | C15H18ClN3O | ||||||||||||
| Molar Mass | 291.78 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
|
||||||||||||
| Reference | [1]. Saito S, et al. A plant growth retardant, uniconazole, is a potent inhibitor of ABA catabolism in Arabidopsis. Biosci Biotechnol Biochem. 2006 Jul;70(7):1731-9. [2]. Zhang M, et al. Uniconazole-induced tolerance of soybean to water deficit stress in relation to changes in photosynthesis, hormones and antioxidant system. J Plant Physiol. 2007 Jun;164(6):709-17. |
Uniconazole
CAS: 83657-22-1 F: C15H18ClN3O W: 291.78
Uniconazole, a plant growth retardant, is a potent inhibitor of abscisic acid (ABA) catabolism with an IC50 of 68 nM aga
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.