| Bioactivity | Umifenovir hydrochloride is a potent, orally active broad-spectrum antiviral with activity against a number of enveloped and non-enveloped viruses. Umifenovir hydrochloride is used as an anti-influenza virus agent. Umifenovir hydrochloride could effectively inhibit the fusion of virus with host cells[1][2]. Umifenovir hydrochloride is an efficient inhibitor of SARS-CoV-2 in vitro. Anti-inflammatory activity[3]. |
| Target | Antiviral; Anti-influenza agent |
| Invitro | Umifenovir hydrochloride exhibits a wide range and potent antiviral activity against a number of viruses including influenza A, B and C viruses, respiratory syncytial virus, adenovirus, parainfluenza type 5 and rhinovirus type 14, avian coronavirus, infectious bronchitis virus and Marek disease virus, hepatitis B virus and hepatitis C virus[1]. |
| In Vivo | Umifenovir (45-180 mg/kg; p.o.; daily for 5 days) suppresses the transcription of influenza viruses (IFV) -associated inflammatory cytokines[2]. Animal Model: |
| Name | Umifenovir hydrochloride |
| CAS | 131707-23-8 |
| Formula | C22H26BrClN2O3S |
| Molar Mass | 513.88 |
| Appearance | Solid |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
| Reference | [1]. Boriskin YS, et al. Arbidol: a broad-spectrum antiviral compound that blocks viral fusion. Curr Med Chem. 2008;15(10):997-1005. [2]. Liu Q, et al. Antiviral and anti-inflammatory activity of arbidol hydrochloride in influenza A (H1N1) virus infection. Acta Pharmacol Sin. 2013;34(8):1075-1083. [3]. Wang X, et al. The anti-influenza virus drug, arbidol is an efficient inhibitor of SARS-CoV-2 in vitro. Cell Discov. 2020;6:28. Published 2020 May 2. |
Umifenovir hydrochloride
CAS: 131707-23-8 F: C22H26BrClN2O3S W: 513.88
Umifenovir hydrochloride is a potent, orally active broad-spectrum antiviral with activity against a number of enveloped
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.