Tris(4-aminophenyl)methane_product_DataBase

Bioactivity	Tris(4-aminophenyl)methane is a triphenylmethane dye. Tris(4-aminophenyl)methane is a weak HCV helicase inhibitor.
Target	HCV helicase
Invitro	Tris(4-aminophenyl)methane (Compound 8) shows weak HCV helicase inhibition (30% inhibition at 100 μM)[1]. To preserve RNA in a biological sample for analysis, the sample is incubated with an RNA preservative capable of precipitating RNA in an aqueous solution, such as a triphenylmethane dye (e.g., methyl green, crystal violet, pararosaniline, or Tris(4-aminophenyl)methane), cresyl violet, or cobalt ions. RNA preservation may be used in an immunostaining assay and other histochemical methods[2].
Name	Tris(4-aminophenyl)methane
CAS	548-61-8
Formula	C19H19N3
Molar Mass	289.37
Appearance	Solid
Transport	Room temperature in continental US; may vary elsewhere.
Storage	4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Reference	[1]. Chen CS, et al. Structure-based discovery of triphenylmethane derivatives as inhibitors of hepatitis C virushelicase. J Med Chem. 2009 May 14;52(9):2716-23.

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