| Bioactivity | Triclofos is a potent, orally active sedative. Triclofos is hydrolyzed rapidly into trichloroethanol (TCEOH) and monosodium phosphate in vivo, which contributes to the sedation[1]. |
| Invitro | Triclofos (0.5-75 µg/mL; pooled plasma) is hydrolyzed rapidly into TCEOH and monosodium phosphate. The average %RSD of the matrix effect is 13.9% for triclofos, 5.6% for trichloroacetic acid (TCA), 8.9% for trichloroethanol (TCEOH) and 14.9% for chloral hydrate (CH)[1]. |
| Name | Triclofos |
| CAS | 306-52-5 |
| Formula | C2H4Cl3O4P |
| Molar Mass | 229.38 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Sato H, et, al. Simple method to detect triclofos and its metabolites in plasma of children by combined use of liquid chromatography tandem-mass spectrometry and gas chromatography-mass spectrometry. Sci Rep. 2019 Jun 26;9(1):9294. |