Bioactivity | Torsemide (Torasemide) is an orally active loop diuretic. Torsemide has anti-aldosterone and vasodilatory effects. Torsemide also can be used for the research of heart failure, renal disease and hepatic cirrhosis[1][1][3]. | ||||||||||||
Invitro | Torsemide binds reversibly to Na+/2Cl-/K+ cotransporter carrier protein, thus reducing or abolishing NaCl reabsorption[1]. | ||||||||||||
Name | Torsemide | ||||||||||||
CAS | 56211-40-6 | ||||||||||||
Formula | C16H20N4O3S | ||||||||||||
Molar Mass | 348.42 | ||||||||||||
Appearance | Solid | ||||||||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
Storage |
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Reference | [1]. Ishido, H., et al. Torasemide for the Treatment of Heart Failure. Cardiovascular & Hematological Disorders-Drug Targets. 2008. 8(2), 127–132. [2]. Goodfriend, T. L., et al. Torsemide inhibits aldosterone secretion in vitro. Life Sciences. 1998. 63(3), PL45–PL50. [3]. H A Friedel, et al. Torasemide. A review of its pharmacological properties and therapeutic potential. Drugs. 1991 Jan;41(1):81-103. |