| Bioactivity | Timiperone has a strong affinity for cerebral dopamine D2 receptor. Timiperone has antipsychotic activity, and inhibits stereotyped behaviour. Timiperone can be used for research of schizophrenia[1][2][3]. |
| Target | dopamine D2 receptor |
| Name | Timiperone |
| CAS | 57648-21-2 |
| Formula | C22H24FN3OS |
| Molar Mass | 397.51 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Sudo K, et al. Disposition of timiperone, 4'-fluoro-4-[4-(2-thioxo-1-benzimidazolinyl)piperidino]butyrophenone, a neuroleptic, in the rat on repeated oral dosage. Xenobiotica. 1981 Oct;11(10):685-91. [2]. Kariya T, et al. A comparison of the clinical effects of timiperone, a new butyrophenone derivative, and haloperidol on schizophrenia using a double-blind technique. J Int Med Res. 1983;11(2):66-77. [3]. Inada, K., et al. First-Generation Antipsychotics as a Bridge to Second-Generation Antipsychotics in the Japanese Pharmaceutical Industry: Mosapramine, Timiperone, Zotepine, and Nemonapride. NeuroPsychopharmacotherapy. Springer, Cham. (2021). |
Timiperone
CAS: 57648-21-2 F: C22H24FN3OS W: 397.51
Timiperone has a strong affinity for cerebral dopamine D2 receptor. Timiperone has antipsychotic activity, and inhibits
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