| Bioactivity | Thiocolchicoside is a competitive γ-aminobutyric acid type A (GABAA) receptor antagonist and glycine receptor agonist in the central nervous system. Thiocolchicoside is a semisynthetic sulfur derivative of colchicoside. Thiocolchicoside is a muscle relaxant and has anti-inflammatory, and analgesic properties[1]. | ||||||||||||
| Target | GABAA) receptor; glycine receptor | ||||||||||||
| Invitro | Thiocolchicoside (0.001, 0.1, 1, 10, 100 μM) reduces the amplitude of eIPSCs in a concentration-dependent manner with this effect being significant at 0.1 μM and maximal at 10 μM[1]. | ||||||||||||
| Name | Thiocolchicoside | ||||||||||||
| CAS | 602-41-5 | ||||||||||||
| Formula | C27H33NO10S | ||||||||||||
| Molar Mass | 563.62 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
|
||||||||||||
| Reference | [1]. Carta M, et al. The muscle relaxant thiocolchicoside is an antagonist of GABAA receptor function in the central nervous system. Neuropharmacology. 2006 Sep;51(4):805-15. |
Thiocolchicoside
CAS: 602-41-5 F: C27H33NO10S W: 563.62
Thiocolchicoside is a competitive γ-aminobutyric acid type A (GABAA) receptor antagonist and glycine receptor agonist i
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.