Bioactivity | Thiacetazone (Thioacetazone) is a thiourea-containing antitubercular agent and is an orally active antibiotic. Thiacetazone has antibacterial action, which inhibits growth of Mycobacterium tuberculosis H37Rv with a MIC value of 0.1 μg/mL[1]. | ||||||||||||
Invitro | Thiacetazone is a prodrug that is activated by the mycobacterial monooxygenase EthA, which is also the activator of two other anti-tuberculosis agents, Ethionamide and Isoxyl[3]. | ||||||||||||
Name | Thiacetazone | ||||||||||||
CAS | 104-06-3 | ||||||||||||
Formula | C10H12N4OS | ||||||||||||
Molar Mass | 236.29 | ||||||||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
Storage |
|