Tetrathiomolybdate_product_DataBase

Bioactivity	Tetrathiomolybdate, an orally active anti-copper agent, reduces copper levels in the body. Tetrathiomolybdate has a protective effect on collagen-induced arthritis in mice. Tetrathiomolybdate also reduces blood sugar, but has no effect on mice with hereditary diabetes (db/db). Tetrathiomolybdate inhibit angiogenesis, also shows antiangiogenic effects in malignant pleural mesothelioma[1][2][3].
In Vivo	Tetrathiomolybdate (0.2 mg/小鼠/天; 口服; 10 周)保护小鼠免受胶原诱导的关节炎，具有预防作用[1]。Tetrathiomolybdate (0.03 mg/mL; 加在水中，8 周)通过减少肿胀和红斑抑制小鼠胶原诱导关节炎的进展[1]。 Animal Model:
Name	Tetrathiomolybdate
CAS	16330-92-0
Formula	MoS42-
Molar Mass	224.22
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Zeng C, et al. Tetrathiomolybdate is partially protective against hyperglycemia in rodent models of diabetes. Exp Biol Med (Maywood). 2008 Aug;233(8):1021-5.

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