| Bioactivity | Tempone (4-Oxo-Tempo) is a stable water-soluble nitro radical. Tempone is widely used as a contrast agent for metabolic activity and hypoxic sensitivity in electron spin resonance spectroscopy, magnetic resonance imaging and dynamic nuclear polarization. Tempone reduces superoxide radicals by mimicking the activity of superoxide dismutase (SOD), thereby reducing the formation of hydroxyl radicals and peroxynitrites. Tempone can be used in the study of ischemia-reperfusion injury and acute renal failure[1]. | ||||||||||||
| CAS | 2896-70-0 | ||||||||||||
| Formula | C9H16NO2* | ||||||||||||
| Molar Mass | 170.23 | ||||||||||||
| Appearance | 固体 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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| Reference | [1]. Patel N S A, et al. TEMPONE reduces renal dysfunction and injury mediated by oxidative stress of the rat kidney[J]. Free Radical Biology and Medicine, 2002, 33(11): 1575-1589. |