| Bioactivity | Taraxinic acid can be found in the roots of Taraxacum flavostylum and Taraxacum lucidum. It is a Tyrosinase inhibitor that dose-dependently inhibits Tyrosinase activity, showing approximately 54.5% inhibition at a concentration of 50 μg/mL. Taraxinic acid has an IC50 of 83.2 μM against melanoma cells A375 and HTB140, and an IC50 of 60.4 μM against melanoma cells WM793, with activity being both dose- and time-dependent. Taraxinic acid holds promise for research in the field of anticancer therapy[1]. |
| CAS | 75911-33-0 |
| Formula | C15H18O4 |
| Molar Mass | 262.30 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Park S I, et al. Tyrosinase inhibitory activity and melanin production inhibitory activity of taraxinic acid from Taraxacum coreanum[J]. Korean Journal of Plant Resources, 2021, 34(4): 368-376. [2]. Michalska K, et al. Further sesquiterpenoids and phenolics from two species of Taraxacum FH Wigg. and cytotoxic activity of taraxinic acid and its derivatives[J]. Phytochemistry Letters, 2019, 30: 296-301. |
Taraxinic acid
CAS: 75911-33-0 F: C15H18O4 W: 262.30
Taraxinic acid can be found in the roots of Taraxacum flavostylum and Taraxacum lucidum. It is a Tyrosinase inhibitor th
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