Bioactivity | Talsaclidine is a muscarinic agonist with preferential neuron-stimulating properties. Talsaclidine is a full agonist at the M1 subtype, and as a partial agonist at the M2 and M3 subtypes[1][2][3][4]. | ||||||||||||
Name | Talsaclidine | ||||||||||||
CAS | 147025-53-4 | ||||||||||||
Formula | C10H15NO | ||||||||||||
Molar Mass | 165.23 | ||||||||||||
Appearance | Liquid | ||||||||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
Storage |
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Reference | [1]. Ensinger HA, et al. WAL 2014--a muscarinic agonist with preferential neuron-stimulating properties. Life Sci. 1993;52(5-6):473-80. [2]. Wienrich M, et al. Pharmacodynamic profile of the M1 agonist talsaclidine in animals and man. Life Sci. 2001 Apr 27;68(22-23):2593-600. [3]. Walland A, et al. In vivo consequences of M1-receptor activation by talsaclidine. Life Sci. 1997;60(13-14):977-84. [4]. Walland A, et al. Compensation of muscarinic bronchial effects of talsaclidine by concomitant sympathetic activation in guinea pigs. Eur J Pharmacol. 1997 Jul 9;330(2-3):213-9. |