PeptideDB

Systemin

CAS: 137181-56-7 F: C85H144N26O28S W: 2010.30

Systemin, an 18-amino acid polypeptide, has been isolated from tomato leaves that is a powerful inducer of over 15 defen
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Bioactivity Systemin, an 18-amino acid polypeptide, has been isolated from tomato leaves that is a powerful inducer of over 15 defensive genes.
Invitro Systemin is readily transported from wound sites and is considered to be the primary systemic signal.The signal transduction pathway that mediates Systemin signaling involves linolenic acid release from membranes and subsequent conversion to jasmonic acid, a potent activator of defense gene transcription. The pathway exhibits analogies to arachidonic acid/prostaglandin signaling in animals that leads to inflammatory and acute phase responses[1]. Systemin, an 18-amino-acid peptide signal. Systemin is cleaved from the C-terminal region of a 200-amino acid precursor protein called proSystemin. Following the cloning of proSystemin gene, which represents a single locus in the tomato genome, several lines of genetic evidence indicate that Systemin acts as an upstream component of wound-induced signaling cascades leading to defense gene expression[2].
Name Systemin
CAS 137181-56-7
Sequence Ala-Val-Gln-Ser-Lys-Pro-Pro-Ser-Lys-Arg-Asp-Pro-Pro-Lys-Met-Gln-Thr-Asp
Shortening AVQSKPPSKRDPPKMQTD
Formula C85H144N26O28S
Molar Mass 2010.30
Transport Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture and light, under nitrogen

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)