| Bioactivity | Symphytine is a pyrrolizidine alkaloid isolated from Symphytum officinale and has carcinogenicity[1]. |
| In Vivo | Symphytine (intraperitoneal injection; 13 mg/kg; 330 days) leads to survival for more than 330 days after the start of injections. Four of 20 rats (20%) had liver tumors: three has hemangioendothelial sarcoma and 1 has liver cell adenoma[1]. Animal Model: |
| Name | Symphytine |
| CAS | 22571-95-5 |
| Formula | C20H31NO6 |
| Molar Mass | 381.46 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Hirono,et al.Induction of Hepatic Tumors in Rats by Senkirkine and Symphytine. J Natl Cancer Inst. 1979 Aug;63(2):469-72. |