Bioactivity | Sultiame is a carbonic anhydrase inhibitor, widely used as an antiepileptic drug. | ||||||||||||
Invitro | Sultiame (Sulthiame) is a sulphonamide, and it may exerts antiepileptic activity by producing a modest intracellular acidosis in central neurons via acting as a carbonic anhydrase inhibitor, thereby reducing the frequency of action potentials and epileptiform bursts[1]. | ||||||||||||
Name | Sultiame | ||||||||||||
CAS | 61-56-3 | ||||||||||||
Formula | C10H14N2O4S2 | ||||||||||||
Molar Mass | 290.36 | ||||||||||||
Appearance | Solid | ||||||||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
Storage |
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Reference | [1]. Milburn-McNulty P, et al. Sulthiame add-on therapy for epilepsy. Cochrane Database Syst Rev. 2015 Oct 28;(10):CD009472. |