| Bioactivity | Sulfaguanidine is an orally active antimicrobial agent/antibiotic of sulfonamide class. Sulfaguanidine can be used for the research of enteric infections such as bacillary dysentery[1][2]. | ||||||||||||
| In Vivo | Sulfaguanidine (2.5 mg/kg; i.v.) exhibits CLt (adult 0.29, neonate 0.14 L/h/kg), AUC0-∞ (adult 8.18, neonate 20.46 μg•h/mL), and Vdss (adult 0.65, neonate 0.59 L/kg) in rats[3].Sulfaguanidine (2.5 mg/kg; p.o.) exhibits absolute bioavailability (adult 12.76%, neonate 57.86%), Cmax (adult 0.41, neonate 3.56 μg/mL), and Tmax (adult 1.67, neonate 1.50 h) in rats[2]. | ||||||||||||
| Name | Sulfaguanidine | ||||||||||||
| CAS | 57-67-0 | ||||||||||||
| Formula | C7H10N4O2S | ||||||||||||
| Molar Mass | 214.24 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. LOWELL A, et, al. THE USE OF SULFAGUANIDINE IN THE TREATMENT OF DYSENTERY CARRIERS. JAMA. 1942 Apr; 118(15):1268-1271. [2]. Mizuno N, et, al. Gastrointestinal absorption of sulfaguanidine in neonatal and adult rats. J Pharmacobiodyn. 1986 Oct;9(10):787-92. |
Sulfaguanidine
CAS: 57-67-0 F: C7H10N4O2S W: 214.24
Sulfaguanidine is an orally active antimicrobial agent/antibiotic of sulfonamide class. Sulfaguanidine can be used for t
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