| Bioactivity | Substance P (4-11), the C-terminus fragment of Substance P (Substance P (HY-P0201)), is a Substance P agonist that shows highly selective for NK1 receptors[1][2]. |
| Invitro | Substance P (4-11) 在浓度为 1 nM-100 nM 时显着刺激体外人 T 淋巴细胞的增殖，通过胸苷和亮氨酸的摄取评估[1]。Substance P (4-11) 在人多形核白细胞 (PMN) 中引发强烈的学发光，具有时间和剂量反应曲线[3]。 |
| Name | Substance P (4-11) |
| CAS | 53749-60-3 |
| Shortening | PQQFFGLM-NH2 |
| Formula | C46H67N11O10S |
| Molar Mass | 966.16 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. D G Payan, et al. Specific stimulation of human T lymphocytes by substance P. J Immunol. 1983 Oct;131(4):1613-5. [2]. L Wang, et al. Substance P induces ion secretion in mouse small intestine through effects on enteric nerves and mast cells. Am J Physiol. 1995 Jul;269(1 Pt 1):G85-92. [3]. P Cornaglia-Ferraris, et al. Sensory neuropeptides (substance P) and 4-11 SP enhance human neutrophils chemiluminescence; the role of L-arginine. Int J Immunopharmacol. 1986;8(4):463-8. |
Substance P (4-11)
CAS: 53749-60-3 F: C46H67N11O10S W: 966.16
Substance P (4-11), the C-terminus fragment of Substance P (Substance P (HY-P0201)), is a Substance P agonist that shows
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