Bioactivity | Sonlicromanol (KH176) hydrochloride, a chemical entity derivative of Trolox, is a blood-brain barrier permeable ROS-redox modulator. Sonlicromanol (KH176) hydrochloride is used in the study for mitochondrial disorders[1]. |
In Vivo | Sonlicromanol (KH176) hydrochloride maintains microstructural coherence in the brain of Ndufs4−/− mice[1]. Animal Model: |
Name | Sonlicromanol hydrochloride |
CAS | 2162149-24-6 |
Formula | C19H29ClN2O3 |
Molar Mass | 368.90 |
Appearance | Solid |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | 4°C, protect from light, stored under nitrogen *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen) |
Reference | [1]. Ria de Haas, et al. Therapeutic effects of the mitochondrial ROS-redox modulator KH176 in a mammalian model of Leigh Disease. Sci Rep. 2017 Sep 15;7(1):11733. |