| Bioactivity | Satratoxin G is a large cyclic mucor toxin. Satratoxin G induces apoptosis by activation of caspase[1][2]. |
| Invitro | Satratoxin G (40 nM, 6 h) 可诱导 HL-60 细胞中 caspase-3 和聚 (adp -核糖) 聚合酶 (PARP) 的裂解[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Satratoxin G 相关抗体: |
| In Vivo | Satratoxin G (500 μg/kg, 鼻内滴注) 可诱导小鼠嗅上皮嗅觉感觉神经元凋亡，并表达 IL-1α、IL-1β、IL-6、TNF-α 和 MIP-2 基因[2]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: |
| CAS | 53126-63-9 |
| Formula | C29H36O10 |
| Molar Mass | 544.59 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Nagase M, et al. Molecular mechanism of satratoxin-induced apoptosis in HL-60 cells: activation of caspase-8 and caspase-9 is involved in activation of caspase-3. Immunol Lett. 2002 Oct 21;84(1):23-7. [2]. Islam Z, et al. Satratoxin G from the black mold Stachybotrys chartarum evokes olfactory sensory neuron loss and inflammation in the murine nose and brain. Environ Health Perspect. 2006 Jul;114(7):1099-107. |