| Bioactivity | S9-A13 is a potent and selective inhibitor SLC26A9, with the IC50 of 90.9 nM, without inhibiting other members of the SLC26 family such as SLC26A3, SLC26A4, and SLC26A6. S9-A13 can inhibits SLC26A9 Cl− currents in cells that lack expression of CFTR[1]. | ||||||||||||
| CAS | 1223771-84-3 | ||||||||||||
| Formula | C20H18ClN3O2S | ||||||||||||
| Molar Mass | 399.89 | ||||||||||||
| Appearance | 固体 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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| Reference | [1]. Sungwoo Jo, et al. The SLC26A9 inhibitor S9-A13 provides no evidence for a role of SLC26A9 in airway chloride secretion but suggests a contribution to regulation of ASL pH and gastric proton secretion. FASEB J. 2022 Nov;36(11):e22534. |
S9-A13
CAS: 1223771-84-3 F: C20H18ClN3O2S W: 399.89
S9-A13 is a potent and selective inhibitor SLC26A9, with the IC50 of 90.9 nM, without inhibiting other members of the SL
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