| Bioactivity | S-palm P0(180–199) (TFA) is a peptide that enhances MHC II-restricted responses. S-palm P0(180–199) (TFA) can be used to establish models of chronic inflammatory demyelinating polyneuropathy (CIDP) and chronic experimental autoimmune neuritis (c-EAN). S-palm P0(180–199) (TFA) is used for studying autoimmune-mediated neuroinflammatory diseases[1][2]. | ||||||
| Sequence | Ala-{Cys(Palm)}-Lys-Arg-Gly-Arg-Gln-Thr-Pro-Val-Leu-Tyr-Ala-Met-Leu-Asp-His-Ser-Arg-Ser | ||||||
| Shortening | A-{Cys(Palm)}-KRGRQTPVLYAMLDHSRS | ||||||
| Formula | C112H191N33O29S2.xC2HF3O2 | ||||||
| Molar Mass | 2528.05 (free base) | ||||||
| Appearance | 固体 | ||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||
| Storage | Sealed storage, away from moisture
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
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| Reference | [1]. Feng Y, et al. Fingolimod ameliorates chronic experimental autoimmune neuritis by modulating inflammatory cytokines and Akt/mTOR/NF-κB signaling. Brain Behav. 2023 Apr;13(4):e2965. [2]. Brun S, et al. Assessing Autophagy in Sciatic Nerves of a Rat Model that Develops Inflammatory Autoimmune Peripheral Neuropathies. Cells. 2017 Sep 18;6(3):30. |
S-palm P0(180–199) TFA
CAS: F: C112H191N33O29S2.xC2HF3O2 W: 2528.05 (free base)
S-palm P0(180–199) (TFA) is a peptide that enhances MHC II-restricted responses. S-palm P0(180–199) (TFA) can be used
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